Breaking down GLP-1
- Clarissa Gannon
- Jun 11
- 1 min read

What Are GLP-1 & DPP-4?
GLP-1 (Glucagon-Like Peptide-1) = a hormone made in the gut that:
Helps regulate blood sugar
Reduces appetite
Slows gastric emptying
Promotes insulin sensitivity
DPP-4 (Dipeptidyl Peptidase-4) = an enzyme that breaks down GLP-1, reducing its effects
What Happens in Perimenopause?
Estrogen decline can reduce GLP-1 production
Increased inflammation + insulin resistance also suppress GLP-1
Some studies suggest DPP-4 activity may increase in aging + metabolic dysfunction → This means less GLP-1 = more cravings, poor blood sugar control, and fat storage
Why It Matters for Fat Loss
Low GLP-1 =
More hunger + cravings
Blood sugar spikes → crashes → fatigue
More fat storage (especially belly fat)
Harder to feel full + satisfied
How to Support GLP-1 Naturally
Eat more fiber (especially resistant starch + prebiotics) Strength train (boosts insulin sensitivity) Manage stress + sleep (cortisol affects GLP-1 signaling) Focus on balanced meals (protein + fat + fiber) Consider nutrients like berberine, magnesium, chromium
EmpowerHER’s Approach
We focus on restoring hormone + metabolic balance by:
Supporting natural GLP-1 production
Reducing inflammation + insulin resistance
Creating sustainable, real-life nutrition strategies
Helping your body feel full, burn fat, and stay balanced





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